Tumor Models

Tumor models:
I have always wanted to investigate
Murine , primate , cell line and human blood tumors!

Leaders in Pharmaceutical Business Intelligence (LPBI) Group

Tumor-Models

Larry H. Bernstein, MD, FCAP, Curator

LPBI

Tumor Models Bridge Mouse-Human Gap

http://www.genengnews.com/gen-articles/tumor-models-bridge-mouse-human-gap/5610/

Revamped Allograft and Innovative Xenograft Models Can Reduce the Risks of Late-Stage Clinical Trials and Increase the Odds of Translational Success

http://www.genengnews.com/Media/images/Article/HorizonDiscovery_CRISPR1417421418.jpg

CRISPR-Cas9 sgRNA in vitro screens can be used to look for genes that when lost induce resistance to a drug (positive screen) or increase sensitivity to a drug (negative screen). The technology might also be a powerful tool for target ID screens in vivo, and looks set to aid in our understanding of tumor development and progression in animal models. [Horizon Discovery]

Precision medicine is all about the two T’s—targets and treatments—targets that emerge from analyses of patient-specific information, and treatments that hit these targets. Both T’s, however, pose difficulties. All too often, insights and drug candidates originating in precision medicine fail to translate into clinical practice.

This reality prompted sober comments…

View original post 1,987 more words

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s